Should we Stress about Ulcer Prophylaxis?

A review of the evidence

The lecture duration is 45min.

0.75 CPD Points, 0.75 CEUs, 0.75 CME credits approval pending.
Accredited by CPDUK, CBRN and Provider Pending.

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Paul Young
Consultant and Researcher in Intensive Care, Wellington, New Zealand
Lecture Summary

Stress ulcer prophylaxis is given commonly to patients in the ICU. However, the choice of which type or drug to use for this purpose or whether widespread use of ulcer prophylaxis is justified is debated. This talk will review current evidence in relation to stress ulcer prophylaxis in the ICU focusing on the recently published PEPTIC trial.

Target Audience

Critical Care Doctors
Experienced or advanced Critical Care Nurses

Learning Objectives:

Upon completion of this activity, you should be able to:

  • Understand the risks and benefits associated with the use of proton pump inhibitors for stress ulcer prophylaxis in the ICU
  • Describe the design and key findings of the PEPTIC trial
  • Develop a practical understanding of when to use stress prophylaxis based on available evidence
  • List key patient subgroups where data suggest that using proton pump inhibitors for stress ulcer prophylaxis may increase mortality risk

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